We describe a recent approach for distinguishing between stochastic and deterministic sources of variability, focusing on the mammalian cell cycle. Variability between cells is often attributed to stochastic noise, although it may be generated by deterministic components. Interestingly, lineage information can be used to distinguish between variability and determinism. Analysis of correlations within a lineage of the mammalian cell cycle duration revealed its deterministic nature. Here, we discuss the sources of such variability and the possibility that the underlying deterministic process (...) is due to the circadian clock. Finally, we discuss the “kicked cell cycle” model and its implication on the study of the cell cycle in healthy and cancerous tissues. (shrink)

The paper outlines the history of the Babi-Baha'i Faith, its main doctrines and practices.

INTRODUCTIONA PRELIMINARY NOTEI. THE PRESENT SCOPE AND SUBSTANCE OF SPERM DONORS’LEGAL AND ETHICAL OBLIGATIONSII. DUTY-BOUND SPERM DONORSA. Delineating the Suggested Ethical ObligationB. Is It the Genetic Link that Morally Binds Sperm Donors by Donor-Duty?III. SUPPORTIVE EVIDENCE FOR RECEPTIVENESS TO DONORDUTY: THE CASE OF DE-ANONYMIZATION OF SPERM DONORSA. Relevant Implications of the Removal of Donor AnonymityIV. ANALOGIZING DONOR-DUTY TO THE DUTY NOT TO INFECT OTHERSA. Mode of TransmissionB. The Public Health PerspectiveC. The Duty to WarnV. COMPETING RIGHTSA. The DCC’s Right to (...) Know Health-Related Information vs. the Donor’s Right to PrivacyB. The DCC’s Right to Know Health-Related Information vs. the Donor’s .. (shrink)

In this Article we propose an analytical framework for allocating responsibility for the protection of worker’s rights in the global labor market. Since production and services have expanded globally, and the state’s ability to protect worker’s rights on the national level has been undermined, the main challenge today is to find the appropriate institutional arrangements that allocate responsibility in a manner that realizes basic labor standards. The Article argues that in the context of a global labor market, responsibility should be (...) perceived in terms of "shared responsibility," whereby responsibility is shared by a complex network of agents and institutions that take part in global production and services. Within these global social networks and connections, labor relations generate a unique type of social connection which implies a special type of commitment and obligation towards workers. We propose four principles to guide the allocation of responsibility for remedying the unjust conditions of workers in the world, based on measures of connectedness, capacity, benefit, and contribution. (shrink)

In this paper, I respond to Philip Atkins’ reply to my attempt to explain why Gettier cases (and Gettier-style cases) are misleading. I have argued that Gettier cases (and Gettier-style cases) are misdealing because the candidates for knowledge in such cases contain ambiguous designators. Atkins denies that Gettier’s original cases contain ambiguous designators and offers his intuition that the subjects in Gettier’s original cases do not know. I argue that his reply amounts to mere intuition mongering and I explain why (...) Gettier cases, even Atkins’ revised version of Gettier’s Case I, still contain ambiguous designators. (shrink)

We argue that a comprehensive theory of reciprocals must rely on a general taxonomy of restrictions on the interpretation of relational expressions. Developing such a taxonomy, we propose a new principle for interpreting reciprocals that relies on the interpretation of the relation in their scope. This principle, the Maximal Interpretation Hypothesis (MIH), analyzes reciprocals as partial polyadic quantifiers. According to the MIH, the partial quantifier denoted by a reciprocal requires the relational expression REL in its scope to denote a maximal (...) relation in REL’s interpretation domain. In this way the MIH avoids a priori assumptions on the available readings of reciprocal expressions, which are necessary in previous accounts. Relying extensively on the work of Dalrymple et al. (Ling Philos 21:159–210, 1998), we show that the MIH also exhibits some observational improvements over Dalrymple et al.’s Strongest Meaning Hypothesis (SMH). In addition to deriving some attested reciprocal interpretations that are not expected by the SMH, the MIH offers a more restrictive account of the way context affects the interpretation of reciprocals through its influence on relational domains. Further, the MIH generates a reciprocal interpretation at the predicate level, which is argued to be advantageous to Dalrymple et al.’s propositional selection of reciprocal meanings. More generally, we argue that by focusing on restrictions on relational domains, the MIH opens the way for a more systematic study of the ways in which lexical meaning, world knowledge and contextual information interact with the interpretation of quantificational expressions. (shrink)

Freedom of association operates as an organizational "meta-norm," appreciated both as an independent value and as a touchstone for the institutional design of the International Labour Organization . Despite the renewed interest of the ILO in various aspects of the norm, its understanding of freedom of association lacks a comprehensive normative framework. This article presents such a conceptual framework and a critical in-depth analysis of current ILO freedom of association jurisprudence. Freedom of association should be understood in terms of equitable (...) dialogue , a term offered and developed herein, as an understanding that is already partly embedded in ILO jurisprudence. (shrink)

I propose a description of one aspect of the philosophical problem about the ontology of colors by formulating and motivating six plausible premises that seem to be hard to deny in isolation but that are jointly incoherent. I briefly sketch a solution and comment on the views presented in this volume from the perspective of the puzzle.

Causality offers the first comprehensive coverage of causal analysis in many sciences, including recent advances using graphical methods. Pearl presents a unified account of the probabilistic, manipulative, counterfactual and structural approaches to causation, and devises simple mathematical tools for analyzing the relationships between causal connections, statistical associations, actions and observations. The book will open the way for including causal analysis in the standard curriculum of statistics, artificial intelligence, business, epidemiology, social science and economics.

Written by one of the preeminent researchers in the field, this book provides a comprehensive exposition of modern analysis of causation. It shows how causality has grown from a nebulous concept into a mathematical theory with significant applications in the fields of statistics, artificial intelligence, economics, philosophy, cognitive science, and the health and social sciences. Judea Pearl presents and unifies the probabilistic, manipulative, counterfactual, and structural approaches to causation and devises simple mathematical tools for studying the relationships between causal (...) connections and statistical associations. Cited in more than 2,100 scientific publications, it continues to liberate scientists from the traditional molds of statistical thinking. In this revised edition, Judea Pearl elucidates thorny issues, answers readers' questions, and offers a panoramic view of recent advances in this field of research. Causality will be of interest to students and professionals in a wide variety of fields. Dr Judea Pearl has received the 2011 Rumelhart Prize for his leading research in Artificial Intelligence and systems from The Cognitive Science Society. (shrink)

The book can also be used as an excellent text for graduate-level courses in AI, operations research, or applied probability.

Are nonconscious processes sufficient to cause false memories of a nonstudied event? To investigate this issue, we controlled and measured conscious processing in the DRM task, in which studying associates causes false memories of nonstudied associates . During the study phase, subjects studied visually masked associates at extremely rapid rates, followed by immediate recall. After this initial phase, nonstudied test words were rapidly presented for perceptual identification, followed by recognition memory judgments. On the perceptual identification task, we found significant priming (...) of nonstudied associates, relative to control words. We also found significant false recognition of these nonstudied associates, even when subjects did not recall this word at study or identify it at test, indicating that nonconscious processes can cause false recognition. These recognition effects were found immediately after studying each list of associates, but not on a delayed test that occurred after the presentation of several intervening lists. Nonconscious processes are sufficient to cause this memory illusion on immediate tests, but may be insufficient for more vivid and lasting false memories. (shrink)

The “received wisdom” in contemporary analytic philosophy is that intuition talk is a fairly recent phenomenon, dating back to the 1960s. In this paper, we set out to test two interpretations of this “received wisdom.” The first is that intuition talk is just talk, without any methodological significance. The second is that intuition talk is methodologically significant; it shows that analytic philosophers appeal to intuition. We present empirical and contextual evidence, systematically mined from the JSTOR corpus and HathiTrust’s Digital Library, (...) which provide some empirical support for the second rather than the first hypothesis. Our data also suggest that appealing to intuition is a much older philosophical methodology than the “received wisdom” alleges. We then discuss the implications of our findings for the contemporary debate over philosophical methodology. (shrink)

This article illustrates how a collaborative research process can successfully engage an underserved minority community to address health disparities. Pacific Islanders, including the Marshallese, are one of the fastest growing US populations. They face significant health disparities, including extremely high rates of type 2 diabetes. This article describes the engagement process of designing patient‐centered outcomes research with Marshallese stakeholders, highlighting the specific influences of their input on a randomized control trial to address diabetes. Over 18 months, an interdisciplinary research team (...) used community‐based participatory principles to conduct patient‐engaged outcomes research that involved 31 stakeholders in all aspects of research design, from defining the research question to making decisions about budgets and staffing. This required academic researcher flexibility, but yielded a design linking scientific methodology with community wisdom. (shrink)

In this paper, I present the results of an experimental study on intuitions about moral obligation (ought) and ability (can). Many philosophers accept as an axiom the principle known as “Ought Implies Can” (OIC). If the truth of OIC is intuitive, such that it is accepted by many philosophers as an axiom, then we would expect people to judge that agents who are unable to perform an action are not morally obligated to perform that action. The results of my experimental (...) study show that participants were more inclined to judge that an agent ought to perform an action than that the agent can perform the action. Overall, participants said that an agent ought to perform an action even when they said that the agent cannot do it. I discuss the implications of these results for the debate over OIC. (shrink)

Everyone has heard the claim, "Correlation does not imply causation." What might sound like a reasonable dictum metastasized in the twentieth century into one of science's biggest obstacles, as a legion of researchers became unwilling to make the claim that one thing could cause another. Even two decades ago, asking a statistician a question like "Was it the aspirin that stopped my headache?" would have been like asking if he believed in voodoo, or at best a topic for conversation at (...) a cocktail party rather than a legitimate target of scientific inquiry. Scientists were allowed to posit only that the probability that one thing was associated with another. This all changed with Judea Pearl, whose work on causality was not just a victory for common sense, but a revolution in the study of the world. (shrink)

This book offers a close and rigorous examination of the arguments for and against scientific realism and introduces key positions in the scientific realism/antirealism debate, which is one of the central debates in contemporary philosophy of science. On the one hand, scientific realists argue that we have good reasons to believe that our best scientific theories are approximately true because, if they were not even approximately true, they would not be able to explain and predict natural phenomena with such impressive (...) accuracy. On the other hand, antirealists argue that the success of science does not warrant belief in the approximate truth of our best scientific theories. This is because the history of science is a graveyard of theories that were once successful but were later discarded. The author eventually settles on a middle ground position between scientific realism and antirealism called "relative realism.". (shrink)

We support Jaswal & Akhtar's interrogation of social motivational accounts of autism and discuss two sources of bias that contribute to how others construe autistic people's communications: an experience-based bias that limits our ability to discern the speaker's action as communicative and a prejudice against the credibility of certain speakers that limits a listener's willingness to believe their testimony.

In this paper, I propose that the debate in epistemology concerning the nature and value of understanding can shed light on the role of scientific idealizations in producing scientific understanding. In philosophy of science, the received view seems to be that understanding is a species of knowledge. On this view, understanding is factive just as knowledge is, i.e., if S knows that p, then p is true. Epistemologists, however, distinguish between different kinds of understanding. Among epistemologists, there are those who (...) think that a certain kind of understanding—objectual understanding—is not factive, and those who think that objectual understanding is quasi-factive. Those who think that understanding is not factive argue that scientific idealizations constitute cognitive success, which we then consider as instances of understanding, and yet they are not true. This paper is an attempt to draw lessons from this debate as they pertain to the role of idealizations in producing scientific understanding. I argue that scientific understanding is quasi-factive. (shrink)

We propose a new definition of actual causes, using structural equations to model counterfactuals. We show that the definition yields a plausible and elegant account of causation that handles well examples which have caused problems for other definitions and resolves major difficulties in the traditional account. 1. Introduction2. Causal models: a review2.1Causal models2.2Syntax and semantics3. The definition of cause4. Examples5. A more refined definition6. DiscussionAAppendix: Some Technical IssuesA.1The active causal processA.2A closer look at AC2(b)A.3Causality with infinitely many variablesA.4Causality in nonrecursive (...) models. (shrink)

In “What’s So Bad about Scientism?” (Mizrahi 2017), I argue that Weak Scientism, the view that “Of all the knowledge we have, scientific knowledge is the best knowledge” (Mizrahi 2017, 354; emphasis in original) is a defensible position. That is to say, Weak Scientism “can be successfully defended against objections” (Mizrahi 2017, 354). In his response to Mizrahi (2017), Christopher Brown (2017) provides more objections against Weak Scientism, and thus another opportunity for me to show that (...) Weak Scientism is a defensible position, which is what I will do in this reply. In fact, I think that I have already addressed Brown’s (2017) objections in Mizrahi (2017), so I will simply highlight these arguments here. (shrink)

In this paper, I argue that appeals to intuition are strong arguments just in case there is an agreement among the relevant philosophers concerning the intuition in question. Otherwise, appeals to intuition are weak arguments.

According to the Ought-Implies-Can principle (OIC), an agent ought to perform a certain action only if the agent can perform that action. Proponents of OIC interpret this supposed implication in several ways. Some argue that the implication in question is a logical one, namely, entailment. Some think that the relation between ‘ought’ and ‘can’ is a relation of presupposition. Still others argue that ‘ought’ conversationally implicates ‘can’. Opponents of OIC offer a variety of counterexamples in an attempt to show that (...) there are cases in which an agent ought to perform a certain action even though she cannot perform that action. Such counterexamples often involve either culpable or nonculpable inability. In cases of culpable inability, the agent renders herself unable to fulfill an obligation. For example, a student is unable to submit a paper on the due date because she procrastinated until it became too late to write a paper by the assigned deadline. In cases of non-culpable inability, the agent somehow becomes unable to fulfill an obligation, through no fault of her own. For example, an agent becomes unable to pay back a loan to a bank because she was robbed on her way to the bank. This paper attempts to offer counterexamples to OIC of a sort different from the one discussed by opponents of OIC so far. If these counterexamples are correct, then they seem to suggest that there are cases in which an agent has an obligation to perform an action even though she may not be able to perform that action, and thus OIC is false. In other words, ‘ought’ does not imply ‘can’. (shrink)

I report the results of a follow-up study, designed to address concerns raised by Kurthy and Lawford-Smith in response to my original study on intuitions about moral obligation (ought) and ability (can). Like the results of the original study, the results of the follow-up study do not support the hypothesis that OIC is intuitive. The results of both studies suggest that OIC is probably not a principle of ordinary moral cognition. As I have argued in my paper, I take this (...) to mean that OIC can no longer be taken as axiomatic. It must be argued for without appealing to intuitions. (shrink)

In this paper, I argue that appeals to intuition are weak arguments because intellectual intuition is an unreliable belief-forming process, since it yields incompatible verdicts in response to the same cases, and since the inference from 'It seems to S that p' to 'p' is unreliable. Since the reliability of intellectual intuition is a necessary condition for strong appeals to intuition, it follows that appeals to intuition are weak arguments.

We propose a new definition of actual causes, using structural equations to model counterfactuals. We show that the definition yields a plausible and elegant account of causation that handles well examples which have caused problems for other definitions and resolves major difficultiesn in the traditional account.

In this paper, I consider the pessimistic induction construed as a deductive argument (specifically, reductio ad absurdum) and as an inductive argument (specifically, inductive generalization). I argue that both formulations of the pessimistic induction are fallacious. I also consider another possible interpretation of the pessimistic induction, namely, as pointing to counterexamples to the scientific realist’s thesis that success is a reliable mark of (approximate) truth. I argue that this interpretation of the pessimistic induction fails, too. If this is correct, then (...) the pessimistic induction is an utter failure that should be abandoned by scientific anti-realists. (shrink)

There is an ongoing methodological debate in philosophy of science concerning the use of case studies as evidence for and/or against theories about science. In this paper, I aim to make a contribution to this debate by taking an empirical approach. I present the results of a systematic survey of the PhilSci-Archive, which suggest that a sizeable proportion of papers in philosophy of science contain appeals to case studies, as indicated by the occurrence of the indicator words “case study” and/or (...) “case studies.” These results are confirmed by data mined from the JSTOR database on research articles published in leading journals in the field: Philosophy of Science, the British Journal for the Philosophy of Science (BJPS), and the Journal for General Philosophy of Science (JGPS), as well as the Proceedings of the Biennial Meeting of the Philosophy of Science Association (PSA). The data also show upward trends in appeals to case studies in articles published in Philosophy of Science, the BJPS, and the JGPS. The empirical work I have done for this paper provides philosophers of science who are wary of the use of case studies as evidence for and/or against theories about science with a way to do philosophy of science that is informed by data rather than case studies. (shrink)

The present study examines the fortuna in the Middle Ages of the Galenic work in fourteen books on Therapeutics, the De Methodo medendi or Therapeutica, known also in the medieval centuries under the titles Ars magna, Megategni and De ingenio sanitatis. After tracing the history of the translations of this text into Latin from the Arabic and the Greek, the study focuses on the De Methodo medendi's place in the medical curricula of the medieval universities. The essay closes with an (...) extensive listing of the medieval manuscript copies of this valuable Galenic treatise. (shrink)

More than 50 years after the publication of Thomas Kuhn’s seminal book, The Structure of Scientific Revolutions, this volume assesses the adequacy of the Kuhnian model in explaining certain aspects of science, particularly the social and epistemic aspects of science. One argument put forward is that there are no good reasons to accept Kuhn’s incommensurability thesis, according to which scientific revolutions involve the replacement of theories with conceptually incompatible ones. Perhaps, therefore, it is time for another “decisive transformation in the (...) image of science by which we are now possessed.” Only this time, the image of science that needs to be transformed is the Kuhnian one. Does the Kuhnian image of science provide an adequate model of scientific practice? If we abandon the Kuhnian picture of revolutionary change and incommensurability, what consequences would follow from that vis-à-vis our understanding of scientific knowledge as a social endeavour? -/- The essays in this collection continue this debate, offering a critical examination of the arguments for and against the Kuhnian image of science as well as their implications for our understanding of science as a social and epistemic enterprise. (shrink)

In his latest attack, even though he claims to be a practitioner of “close reading” (Wills 2018b, 34), it appears that Wills still has not bothered to read the paper in which I defend the thesis he seeks to attack (Mizrahi 2017a), or any of the papers in my exchange with Brown (Mizrahi 2017b; 2018a), as evidenced by the fact that he does not cite them at all. This explains why Wills completely misunderstands Weak Scientism and the arguments (...) for the quantitative superiority (in terms of research output and research impact) as well as qualitative superiority (in terms of explanatory, predictive, and instrumental success) of scientific knowledge over non-scientific knowledge. (shrink)

In this paper, I argue that, contrary to common opinion, a counterexample against a philosophical theory does not amount to conclusive evidence against that theory. Instead, the method of counterexamples allows for the derivation of a disjunction, i.e., ‘either the theory is false or an auxiliary assumption is false’, not a negation of the target theory. This is so because, whenever the method of counterexamples is used in an attempt to refute a philosophical theory, there is a crucial auxiliary assumption (...) that needs to be taken into account. The auxiliary assumption is that making intuitive judgments in response to hypothetical cases about the subject matter in question (e.g., knowledge or proper names) is a good method for finding out truths about that subject matter. Without good reasons to think that this assumption is warranted, the negation of a philosophical theory whose content is alleged to be in conflict with the content of an intuition cannot be justifiably derived using an argument that employs the method of counterexamples. (shrink)

It is a common view among philosophers of science that theoretical virtues (also known as epistemic or cognitive values), such as simplicity and consistency, play an important role in scientific practice. In this article, I set out to study the role that theoretical virtues play in scientific practice empirically. I apply the methods of data science, such as text mining and corpus analysis, to study large corpora of scientific texts in order to uncover patterns of usage. These patterns of usage, (...) in turn, might shed some light on the role that theoretical virtues play in scientific practice. Overall, the results of this empirical study suggest that scientists invoke theoretical virtues explicitly, albeit rather infrequently, when they talk about models (less than 30%), theories (less than 20%), and hypotheses (less than 15%) in their published works. To the extent that they are mentioned in scientific publications, the results of this study suggest that accuracy, consistency, and simplicity are the theoretical virtues that scientists invoke more frequently than the other theoretical virtues tested in this study. Interestingly, however, depending on whether they talk about hypotheses, theories, or models, scientists may invoke one of those theoretical virtues more than the others. (shrink)

In this paper, I report the results of an empirical study, which was designed to test the following hypotheses: (H1) Many philosophers find scientism threatening because they see it as a threat to the future of philosophy as a major in colleges and universities; (H2) Many philosophers find scientism threatening because they see it as a threat to the soul or essence of philosophy as an a priori discipline. My results provide some empirical evidence in support of H2. These results (...) are also in line with the results of other empirical studies that point to a methodological shift in philosophy from the armchair to the laboratory. (shrink)